Dormosedan – Veterinary Sedative & Analgesic for Horses

What Is Dormosedan?

Dormosedan Injectable Solution is a synthetic alpha‑2 adrenoreceptor agonist developed by Zoetis. Its active ingredient, detomidine hydrochloride (10 mg/mL), provides both sedation and analgesia in horses. Dormosedan is widely trusted by veterinarians for procedures requiring calmness, pain relief, and safe handling.

How Dormosedan Works

• Alpha‑2 agonist action: Reduces nerve activity, producing sedation and pain relief.
• Sedation: Horses become calm and manageable for procedures.
• Analgesia: Provides pain relief for minor surgical and diagnostic interventions.
• Rapid onset: IV administration begins working in 2–4 minutes; IM in 3–5 minutes.
• Duration: Sedation lasts 30–90 minutes; analgesia lasts 30–75 minutes depending on dose.

Indications

Dormosedan is indicated for:

• Minor surgical procedures: Suturing lacerations, castrations.
• Diagnostic procedures: Bronchoscopy, nasogastric intubation, rectal palpation.
• Pain relief: Abdominal pain and colic management.
• Handling fractious horses: Ensures safety during examinations.

Benefits

• Safe and predictable sedation for horses.
• Dual action: Provides both sedation and analgesia.
• Versatile use: Suitable for diagnostic, surgical, and handling procedures.
• Trusted brand: Manufactured by Zoetis, a leader in veterinary pharmaceuticals.
• Global recognition: Approved in multiple countries for equine use.

Administration & Dosage

• Concentration: 10 mg/mL detomidine hydrochloride.
• Route: Intravenous (IV) or intramuscular (IM).
• Dosage:
  • 20 mcg/kg (1 mL/500 kg horse) → sedation for 30–90 minutes.
  • 40 mcg/kg (2 mL/500 kg horse) → deeper sedation for 1.5–2 hours.
• Onset: IV 2–4 minutes; IM 3–5 minutes.
• Precaution: Analgesia duration is shorter than sedation; monitor animals closely.

Safety & Precautions

• Side effects: Bradycardia, sweating, piloerection, mild ataxia.
• Contraindications: Avoid in animals with cardiovascular disease or respiratory compromise.
• Veterinary supervision required: Federal law restricts Dormosedan to licensed veterinarians.
• Withdrawal periods: Must be observed in food‑producing animals.

Global Availability

Global Vet Meds ensures secure and reliable access to Dormosedan across multiple regions:

• UK & Ireland – Veterinary‑approved sourcing with fast delivery.
• Canada & USA – Licensed distribution with compliance to local regulations.
• Australia & New Zealand – Safe import channels for equine use.
• Europe (Germany, France, Spain, Portugal, Switzerland, etc.) – EU‑compliant supply chain with multilingual support.

Why Choose Global Vet Meds?

• Authenticity Guaranteed: Genuine Dormosedan injections sourced from Zoetis.
• Worldwide Shipping: Covering major European countries, UK, Canada, and Australia.
• Expert Support: Guidance on safe handling, dosage, and administration.
• Customer Confidence: Transparent policies, secure checkout, and responsive service.

Dormosedan Injectable is indicated for use as a sedative and analgesic to facilitate minor surgical and diagnostic procedures in mature horses and yearlings. It has been used successfully for the following: to calm fractious horses, to provide relief from abdominal pain, to facilitate bronchoscopy, bronchoalveolar lavage, nasogastric intubation, nonreproductive rectal palpations, suturing of skin lacerations, and castrations. Additionally, an approved, local infiltration anesthetic is indicated for castration.

Greater a₂ selectivity and dosing flexibility

• • DORMOSEDAN Injectable allows dosing flexibility so you can accurately regulate the depth and length of sedation and analgesia
  • Simple dosing: 1 or 2 mL per 1,100 lbs horse IM or IV
  • Whether administered IV or IM, DORMOSEDAN produces rapid onset of effect (5 minutes for IV,10 to15 minutes for IM)
  • Xylazine can bind with a₁ and non-a₂ receptor sites, producing variable neurological effects⁴
  • DORMOSEDAN’s potency is 80 to 100 times greater than xylazine in sedation and analgesic effect⁵
  • Effects may be maintained up to 2 hours depending on dose level and route of administration, with analgesia being more pronounced following IV injection
  • Additional dosing prolongs not deepens sedation
  • Pfizer Animal Health does not recommend the use at higher than the approved label dosed

Dosage and Administration

For Sedation

AdministerInjectable IV or IM at the rates of 20 or 40 mcg detomidine hydrochloride per kg of body weight (0.2 or 0.4 mL of D per 100 kg or 220 lb), depending on the depth and duration of sedation required. Onset of sedative effects should be reached within 2-4 minutes after IV administration and 3-5 minutes after IM administration. Twenty mcg/kg will provide 30-90 minutes of sedation and 40 mcg/kg will provide approximately 90 minutes to 2 hours of sedation.

For Analgesia

Administer IV at the rates of 20 or 40 mcg detomidine hydrochloride per kg of body weight (0.2 or 0.4 mL of nn per 100 kg or 220 lb), depending on the depth and duration of analgesia required. Twenty mcg/kg will usually begin to take effect in 2-4 minutes and provide 30-45 minutes of analgesia. The 40 mcg/kg dose will also begin to take effect in 2-4 minutes and provide 45-75 minutes of analgesia.