Equioxx Tablets 57mg – Powerful Advanced Equine Osteoarthritis Pain Relief
Equioxx Tablets 57mg contain firocoxib, a prescription non-steroidal anti-inflammatory drug (NSAID) in the COXIB class. The product is approved for horses for the control of pain and inflammation associated with osteoarthritis. The U.S. labeling specifies one 57mg tablet orally once daily for horses weighing 800–1,300 lb, for up to 14 days.
For Global Vet Meds, this page provides detailed product information about Equioxx Tablets 57mg, including its active ingredient, veterinary uses, administration considerations, precautions and responsible purchasing guidance.
What Is Equioxx Tablets 57mg?
Equioxx Tablets 57mg are chewable firocoxib tablets formulated specifically for horses. Firocoxib is a COX-2-selective NSAID designed to help control pain and inflammation associated with osteoarthritis.
Osteoarthritis can affect horses of different ages and disciplines and may be associated with stiffness, lameness, reduced mobility and reluctance to exercise.
Product Overview
| Product Detail | Information |
|---|---|
| Product | Equioxx Tablets |
| Strength | 57mg firocoxib per tablet |
| Drug class | COXIB / NSAID |
| Species | Horses |
| Primary indication | Pain and inflammation associated with osteoarthritis |
| Route | Oral |
| Frequency | Once daily under the U.S. label |
| Maximum U.S. treatment duration | Up to 14 days |
| Prescription status | Prescription veterinary medicine |
Table of Contents
- What Is Equioxx Tablets 57mg?
- Equioxx for Horses
- Firocoxib and Osteoarthritis
- How Equioxx Helps Manage Joint Pain
- Signs of Osteoarthritis in Horses
- Equioxx Dosage and Administration
- Safety and Precautions
- Equioxx and Other NSAIDs
- Equioxx for Competition Horses
- Storage and Handling
- Where To Buy Equioxx Tablets 57mg Online
- Frequently Asked Questions
Equioxx for Horses
Equioxx Tablets 57mg are specifically formulated for horses. The FDA-approved indication is control of pain and inflammation associated with osteoarthritis.
Osteoarthritis can affect a horse’s ability to move comfortably and may become noticeable through changes such as:
- Stiffness
- Lameness
- Reduced stride
- Reluctance to exercise
- Difficulty with transitions
- Reduced activity
- Changes in gait
A veterinary examination can help determine whether osteoarthritis is responsible for these signs.
Firocoxib and Osteoarthritis
Firocoxib belongs to the COXIB class of NSAIDs. It selectively inhibits the COX-2 enzyme involved in pathways associated with pain and inflammation.
The objective of treatment is to control the clinical signs associated with osteoarthritis while allowing the veterinarian to monitor the horse for potential adverse effects.
Equioxx is not a cure for the underlying degenerative changes associated with osteoarthritis. Long-term management may involve veterinary evaluation, exercise modification, weight management and other appropriate joint-care strategies.
How Equioxx Helps Manage Joint Pain
Equioxx is intended to reduce pain and inflammation associated with equine osteoarthritis.
Boehringer Ingelheim describes the product as providing once-daily control of osteoarthritis-associated pain and inflammation.
Response can vary between horses. Treatment should therefore be monitored by a veterinarian, particularly if the horse requires repeated or extended pain-management strategies.
Signs of Osteoarthritis in Horses
Horse owners may notice several possible signs of joint discomfort, including:
- Lameness
- Stiffness after rest
- Reduced willingness to work
- Difficulty walking, trotting or cantering
- Shortened stride
- Changes in performance
- Joint heat or swelling
- Reduced mobility
These signs can also occur with other musculoskeletal conditions. A diagnosis should therefore be established before assuming osteoarthritis is the cause.
Equioxx Tablets 57mg Dosage and Administration
According to the U.S. product label, the recommended dosage is one 57mg tablet orally once daily for horses weighing 800–1,300 lb, for up to 14 days. The tablet may be given with food.
The FDA label states that the overall duration of treatment with firocoxib formulations in horses, including Equioxx tablets, injection or oral paste, should not exceed 14 days under that labeling.
Do not extend treatment, change the dose or combine firocoxib products without veterinary direction.
Safety and Precautions
Equioxx is an NSAID and should be used under veterinary supervision.
The FDA warns that serious NSAID-related adverse effects can occur with or without warning. Potential concerns include gastrointestinal, kidney and liver effects, while firocoxib treatment has also been associated with erosions or ulcers involving the mouth and surrounding tissues.
Treatment should be stopped and veterinary advice sought if concerning signs such as:
- Loss of appetite
- Colic
- Abnormal feces
- Lethargy
- Mouth or facial lesions
- Other unexpected reactions
are observed.
Equioxx and Other NSAIDs
Equioxx should not be casually combined with other NSAIDs or corticosteroids.
Boehringer Ingelheim specifically advises avoiding use with other NSAIDs, corticosteroids and nephrotoxic medications.
Tell your veterinarian about every medication and supplement the horse is receiving, including:
- Phenylbutazone
- Flunixin meglumine
- Aspirin
- Diclofenac
- Ketoprofen
- Other NSAIDs
- Corticosteroids
- Kidney-affecting medicines
- Dietary supplements
Equioxx for Competition Horses
Owners of racehorses and competition horses should check the current rules of the relevant governing organization before administering Equioxx Tablets 57mg.
Prescription status and competition eligibility are separate issues. A medicine can be legally prescribed while still being restricted or subject to withdrawal or detection requirements in competition.
Always consult the applicable medication-control rules and veterinarian.
Storage and Handling
Keep Equioxx Tablets 57mg secured and according to the manufacturer’s current storage instructions.
The FDA label specifically warns owners to keep Equioxx out of reach of dogs and other pets because accidental ingestion or overdose can be dangerous.
Also:
- Check the expiration date.
- Keep tablets in their appropriate packaging.
- Keep medication away from children.
- Do not give the medication to humans.
- Follow veterinary instructions for administration.
Where To Buy Equioxx Tablets 57mg Online
If you are looking to buy Equioxx Tablets 57mg online, verify the exact product, strength and regulatory requirements before ordering.
Global Vet Meds provides information for customers researching equine medicines and horse-health products.
Before purchasing, confirm:
- Equioxx Tablets 57mg
- Active ingredient: firocoxib
- Tablet strength
- Manufacturer
- Intended species
- Expiration date
- Storage requirements
- Prescription requirements
- Local veterinary regulations
- Competition medication requirements
Equioxx is a prescription veterinary medicine in the United States and should be used only under veterinary direction.
Frequently Asked Questions
What are Equioxx Tablets 57mg?
Equioxx Tablets 57mg are firocoxib-containing veterinary NSAID tablets approved for horses to control pain and inflammation associated with osteoarthritis.
What is the active ingredient in Equioxx?
The active ingredient is firocoxib, a COXIB-class NSAID.
What are Equioxx Tablets used for?
Equioxx Tablets are indicated for controlling pain and inflammation associated with osteoarthritis in horses.
What is the Equioxx 57mg dosage?
The U.S. label recommends one 57mg tablet orally once daily for horses weighing 800–1,300 lb, for up to 14 days.
Can Equioxx be given with phenylbutazone?
Equioxx should not be combined with other NSAIDs such as phenylbutazone unless specifically directed by a veterinarian. Boehringer Ingelheim advises avoiding concurrent use with other NSAIDs and corticosteroids.
Can Equioxx be used long term?
The U.S. tablet label specifies treatment for up to 14 days. Any longer-term pain-management strategy requires veterinary reassessment and should not be undertaken by simply extending the labeled course.
Is Equioxx safe for every horse?
No. Horses should receive a veterinary history and physical examination before NSAID treatment. The safety of Equioxx has not been established in horses under one year of age or in breeding, pregnant or lactating horses.
Where can I buy Equioxx Tablets 57mg?
When purchasing online, verify the product strength, manufacturer, prescription requirements and applicable veterinary regulations. Equioxx is a prescription veterinary product in the United States.
Equioxx (firocoxib) has been the only coxib non-steroidal anti-inflammatory drug (NSAID) approved for use in horses. Now, this once-daily treatment to control joint pain and inflammation associated with equine osteoarthritis, is approved by the FDA in tablet form, and it will be available in the market early fall.
EQUIOXX is the only NSAID approved for use up to 14 days by both the AQHA and USEF1,2† and now gives the choice of three formulations, depending on the specific need of the horse. Injection is best to initiate therapy, while the Paste is a convenient form for accurate dosing, especially for small horses and performance horses. And now, Tablets are easy to administer, with or without feed.
“Veterinarians and horse owners have been waiting for a tablet option o from Merial,” said Hoyt Cheramie, DVM, MS, Manager, Merial Large Animal Veterinary Services.
“The FDA approval process is very stringent, and we are proud to bring this new tablet formulation to market for horses. Having all three formulations allows for consistent therapy with the same active ingredient.”
“When a horse needs relief from osteoarthritis at home or at a show, owners should partner with their veterinarians to determine the best treatment options, be diligent about choosing the right formulations, and follow dosing directions,” said Cheramie. He noted that when it comes to giving medications to performance horses, owners, trainers and veterinarians should read the rules specific to each association or show, ensuring they are in compliance.
EQUIOXX Tablets will be available by prescription only. Veterinarians are encouraged to reach out to their Merial Sales Representatives to get more details about the upcoming availability of this new formulation.
IMPORTANT SAFETY INFORMATION: As with any prescription medication, prior to use, a veterinarian should perform a physical examination and review the horse’s medical history. A veterinarian should advise horse owners to observe for signs of potential drug toxicity. As a class, nonsteroidal anti-inflammatory drugs may be associated with gastrointestinal, hepatic and renal toxicity. Use with other NSAIDs, corticosteroids or nephrotoxic medication should be avoided. EQUIOXX has not been tested in horses less than 1 year of age or in breeding horses, or pregnant or lactating mares. For additional information, please refer to the prescribing information or visit
About Merial
Merial is a world-leading, innovation-driven animal health company, providing a comprehensive range of products that focus on disease prevention and overall health and wellness in animals. Merial has three main business areas: pets, farm animals, and veterinary public health, and our health solutions target more than 200 diseases and conditions across a variety of species. Merial employs 6,900 people and operates in more than 150 countries worldwide with over €2.5 billion of sales in 2015. Merial is a Sanofi company. For more information, please see
† EQUIOXX Injection may be used for five of the 14 days.
1 American Quarter Horse Association. Conditionally permitted therapeutic medications.
Official Handbook of Rules and Regulations. 2016:45-48.
2 United States Equestrian Federation. Guidelines for Drugs and Medications. 2015:8-9.
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